Understanding Lithium Toxicity and Essential Nursing Interventions Lithium, a mood-stabilizing medication commonly used to manage bipolar disorder, can be highly effective in stabilizing mood and preventing relapses. However, it also carries the risk of toxicity if not carefully monitored. The therapeutic medication serum level of lithium is 0.6 to 1.2 mEq/L. The cause of an increase lithium level includes decreased sodium intake, fluid and electrolyte loss associated with excessive sweating, de