Years before he conducted the research that would earn him a Nobel Prize in Physiology and Medicine, Shinya Yamanaka, MD, ...

A recent study comparing young and aged mouse intestinal tissues revealed a delicate balance between IFN-γ signaling and ERK/MAPK signaling as crucial for maintaining the intestinal stem cell ...

A stem cell-derived intestine model reveals glycyrrhizin as a potential treatment for inflammatory bowel disease.

In a key advance for regenerative medicine and gut health, scientists from Duke-NUS Medical School and Nanyang Technological University, Singapore (NTU Singapore) have uncovered a precise and ...

Drosophila melanogaster has long served as a powerful model for dissecting the principles of tissue homeostasis and regeneration. Within the adult midgut, intestinal stem cells (ISCs) perform the ...

Intestinal Stem Cells (ISCs) derived from a patient's own cells have garnered significant attention as a new alternative for treating intractable intestinal diseases due to their low risk of rejection ...

When inflammation damages the intestinal lining, differentiated enterocytes and crypt base columnar stem cells (CBCs) revert to a regenerative, fetal-like state and form revival stem cells (revSCs).

Years before he conducted the research that would earn him a Nobel Prize in Physiology and Medicine, Shinya Yamanaka ...

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...

A new study reported in Nature has determined that the amino acid cysteine could promote regeneration among cells in the small intestine. The work showed that cysteine can activate an immune signaling ...