For the roughly 8.7 million people worldwide living with type 1 diabetes, daily life revolves around a problem their bodies ...

With just one shot, scientists have slashed cholesterol levels in mice. The treatment lasted for at least half their lives. The shot may sound like gene editing, but it’s not. Instead, it relies on an ...

Scientists from Vilnius University's (VU) Life Sciences Center (LSC) have discovered a unique way for cells to silence specific genes without cutting DNA. This research, led by Prof. Patrick Pausch ...

In a recent study published in the journal Nature, scientists used mouse models to test whether in vivo gene silencing is sustained after transient delivery and expression of engineered ...

Mouse data from a new study published Feb. 28 in Nature and sponsored in part by Chroma Medicine suggest that epigenetic gene silencing can suppress the target gene for nearly a year, providing new ...

Silence Therapeutics designs and develops siRNAs (short interfering RNAs) to address unmet patient need across a wide range of diseases with a genetic basis. In this interview with STAT Brand Studio, ...

Epigenetics, the dynamic regulation of genetic expression, involves complex molecular mechanisms. While the process of gene silencing by methylating the H3K27 position in histones is understood, not ...

The discovery of RNAi dates back to the 1990s when researchers observed unexpected gene silencing in plants and fungi. In 1998, Andrew Fire and Craig Mello published a groundbreaking study ...